- Claude Bernard -
“The joy of discovery is certainly the liveliest that the mind of man can ever feel”
Pancreas, Kidney and Skin Regeneration
Phuc Van Pham (Editor)
March 04, 2017
This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in diabetes, kidney and wound treatment. All chapters are contributed by pre-eminent scientists in the field and covers such topics as stem cells and cell therapy in the treatment of diabetes mellitus, kidney failure, wound and other skin aging diseases, characteristics of some kinds of stem/progenitor cells for therapy, future directions of the discussed therapies and much more.
Pancreas, Kidney and Skin Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.
Phuc Van Pham (Editor)
December 31, 2016
This invaluable resource explores the regenerative potential of stem cells in the nervous system, with a focus on clinical applications. The expertly authored chapters discuss cell-based therapies for spinal cord injury and regeneration, traumatic brain injury, glioblastoma, Parkinson's Disease, ischemic stroke, cell banking, human embryonic stem cells and related concerns, harvesting of adipose tissue, and more. These topics are contextualized within a discussion of future directions of these therapies.
Neurological Regeneration, part of Springer’s Stem Cells in Clinical Applications series, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, neurology, regenerative medicine or tissue engineering.
Bone and Cartilage Regeneration
Phuc Van Pham (Editor)
July 02, 2016
This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more.
Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.
Stem Cell Processing
Phuc Van Pham (Editor)
July 31, 2016
This invaluable resource delineates procedures for development and use of stem cells in the laboratory and explores the potential for clinical applications. The text discusses mesenchymal stem cell isolation, isolation of adipose derived stem cells, new trends of induced pluripotent stem cells in disease treatment, cord blood banking, future directions of the discussed therapies and much more. The chapters are contributed by preeminent scientists in the field and present a comprehensive picture of stem cell processes, from development in the laboratory to effects and side-effects of clinical application.
Stem Cell Processing and the other books in the Stem Cells in Clinical Applications series, edited by Dr. Phuc Van Pham, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.
Liver, Lung and Heart Regeneration
Phuc Van Pham (Editor)
December 31, 2016
This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in liver, lung and heart regeneration. All chapters are contributed by pre-eminent scientists in the field and covers such topics as cell therapy in the treatment of cirrhosis and other liver, heart and lung diseases, characteristics of hepatic progenitor cells, future directions of the discussed therapies and much more.
Liver, Lung and Heart Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.
Advances in Stem Cell Therapy: Bench to Bedside
Editors: El-Badri, Nagwa (Ed.)
October 25, 2016
The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.
Regenerative Medicine: Using Non-Fetal Sources of Stem Cells
Editors: Bhattacharya, Niranjan, Stubblefield, Phillip G. (Eds.)
September 21, 2015
This book represents a major contribution to the emerging science of regenerative medicine using non-fetal sources of stem cells. The Editors, Dr Niranjan Bhattacharya and Professor Phillip Stubblefield, have brought together some of the most pre-eminent scientists working on regenerative medicine to share information on currently ongoing work in this area alongside unpublished observations that will help to shape the contours of future therapies.
Regenerative Medicine: Using Non-Fetal Sources of Stem Cells discusses the potential clinical and therapeutic applications using non-fetal stem cells as well as providing instruction on the collection, isolation and characterization of stem cells from various non-fetal sources, such as menstrual blood, adipose tissue, breast milk and uprooted decidual teeth.
This book will be an invaluable resource for both active researches and those entering the field. The Editors truly hope that the text will act as a stimulant to professionals and clinical scientists, who may be inspired to further the work of the pioneering scientists who have contributed to this volume.
The Encyclopedia of Information Science and Technology, Third Edition
Edited by Mehdi Khosrow-Pour
June 24, 2014
Information acquisition and management has always had a profound impact on societal and organizational progression. However, as computing dramatically advances the level of intelligence associated with management technologies, the breadth of their dispersal, and ultimately the impact of the information itself, the utilization and management of information science and technology also gains profound importance. This change-driven environment creates a critical need for a comprehensive, up-to-date reference encompassing the full range of concepts, issues, methods, technologies, and trends associated with the field.
The Encyclopedia of Information Science and Technology, Third Edition is a 10-volume compilation of authoritative, research-based articles contributed by thousands of researchers and experts from all over the world. This discipline-defining encyclopedia will serve research needs in numerous fields that are affected by the rapid pace and substantial impact of technological change. With an emphasis on modern issues and the presentation of potential opportunities, prospective solutions, and future directions in the field, it is a relevant and essential addition to any academic library’s reference collection.
Human Fetal Growth and Development: First and Second Trimesters
Editors: Bhattacharya, Niranjan, Stubblefield, Phillip G. (Eds.)
September 27, 2016
This unique book delves into the mysteries of human fetal growth and maturation. Growing knowledge in genetics indicates that factors that impact on/influence fetal growth and maturation may have a role in determining a person’s health and disease in later years. Placental, maternal, environmental, nutrient as well as fetal genome factors each play a role in producing a healthy, unhealthy or abnormal baby. A study of fetal growth and maturation is therefore basic to the understanding of why fetal growth problems occur, what implications these can have for adult disease, and how clinical intervention can help to reverse growth problems. The present study will be comprehensive and will be a major contribution to the fields of gynecology, genetics, obstetrics, biochemistry, molecular biology and clinical medicine. It will include cutting edge research in the field as well as explorations on clinical interventions in fetal growth, which will not only add to existing knowledge but also prompt future research.
The two Editors are distinguished in their fields and both have extensive clinical and research experience. They felt that they could use their expertise to create a book that will help students, practitioners, researchers and others to understand the subject of gestation, growth and maturation and its implications from a multi-dimensional point of view, which will help them develop their own expertise in a cutting-edge and developing field. They have brought toget
her medical scientists, clinical practitioners, embryologists, endocrinologists, immunologists, gynecologists, obstetricians, reproductive and molecular biologists, geneticists and many others to create a state-of-the-art book on a subject with increasing demand for further knowledge. It aims to integrates different disciplines to give a holistic view of human fetal growth maturation.
Stem Cells and Good Manufacturing Practices: Methods, Protocols, and Regulations
Editors: Turksen, Kursad (Ed.)
November 29, 2015
This volume collects a series of protocols describing the kinds of infrastructures, training, and standard operating procedures currently available to actualize the potential of stem cells for regenerative therapies. Stem Cells and Good Manufacturing Practices: Methods, Protocols, and Regulations pulls together key GMP techniques from laboratories around the world. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Inclusive and authoritative, Stem Cells and Good Manufacturing Practices: Methods, Protocols, and Regulations will be an invaluable resource to both basic and clinical practitioners in stem cell biology.
Omics Approaches in Breast Cancer: Towards Next-Generation Diagnosis, Prognosis and Therapy
Editors: Barh, Debmalya (Ed.)
September 23, 2014
Breast cancer is the most common cancer in females that accounts for highest cancer specific deaths worldwide. In the last few decades research has proven that breast cancer can be treated if diagnosed at early stages and proper therapeutic strategy is adopted. Omics-based recent approaches have unveiled the molecular mechanism behind the breast tumorigenesis and aid in identification of next-generation molecular markers for early diagnosis, prognosis and even the effective targeted therapy. Significant development has taken place in the field of omics in breast cancer in the last decade. The most promising omics approaches and their outcomes in breast cancer have been presented in this book for the first time. The book covers omics technologies and budding fields such as breast cancer miRNA, lipidomics, epigenomics, proteomics, nutrigenomics, stem cell, pharmacogenomics and personalized medicine and many more along with conventional topics such as breast cancer management etc. It is a research-based reference book useful for clinician-scientists, researchers, geneticists and health care industries involved in various aspects of breast cancer. The book will also be useful for students of biomedicine, pathology and pharmacy.
Stem Cells and Cancer Stem Cells, Volume 4: Therapeutic Applications in Disease and Injury
Editors: Hayat, M.A. (Ed.)
December 04, 2012
Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem cells, induced pluripotent stem cells, human hair follicle stem cells, bone marrow-derived human mesenchymal stem cells, adipose-derived stem cells, periodontal/progenitor cells, cancer stem cells, and breast cancer stem cells. Because human embryonic stem cells possess the potential to produce unlimited quantities of any human cell type, considerable focus is placed on this type of stem cells in this volume. The role of cancer stem cells, specifically in breast cancer is explained. Transplantation of mesenchymal stem cells to aid the injured brain is included. Immune recovery after stem cells transplantation in severe combined immunodeficiency patients is described. The role of mesenchymal stem cells in enhancing the growth and metastasis of colon cancer is discussed. Clinical application of human follicle stem cells is presented. Treatment of malignant gliomas using genetically-modified neural stem cells as a marker is discussed. The impact of cancer stem cell hypothesis on designing new cancer therapies is explained. In the field of regenerative medicine, the use of stem cells in the repair of the central nervous system, tendon injury, and as a cardiac regenerative medicine is described. The role of DNA methylation in maintaining stemness induced pluripotent stem cells from human extraembryonic amnion cells is discussed. Insights on the understanding of molecular pathways involved in tumor biology are explained, which lead to the development of effective drugs. Information on pathways, such as hedgehog, facilitates targeted therapies in cancer.
Biomedical Tissue Culture
Edited by Luca Ceccherini-Nelli and Barbara Matteoli
August 18, 2014
This book describes many aspects of tissue culture models in an extensive manner. The book includes many topics like, the development of cultural methods to produce massive neuronal syncytial connections and induce their fusion with formation of bi- and multinucleated cells, the applicability in research of cell lines derived from the cultivation of placenta derived cells and cell populations with properties of progenitor/stem cells, the procedures that may be used to regenerate cartilage tissue with appropriate mechanical properties, the improvements made in the use of cell culture for virus isolation, tissue-based models for HCV replication in vitro, cultures to study the pathogenicity of enteropathogenic bacteria, the use of viral DNA and cDNA Array in the diagnosis of respiratory tract infections (RTI) in comparison with routine diagnosis methods.
The Research and Biology of Cancer I
Edited by iConcept Press
June 18, 2013
Cancer is a broad group of diseases involving unregulated cell growth, in which cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. Cancer may also spread to different parts of the body through the lymphatic system or the bloodstream. The Research and Biology of Cancer discusses some recent advances in cancer research. There are totally two volumes: Volume I mainly discusses the roles of some important enzymes and proteins in cancers, whereas Volume II discusses different types of cancers, including head and neck cancer, oral cancer, kidney cancer, colon cancer, and thyroid cancer.
Stem Cells in Clinic and Research
Edited by Ali Gholamrezanezhad
April 23, 2012
Based on our current understanding of cell biology and strong supporting evidence from previous experiences, different types of human stem cell populations are capable of undergoing differentiation or trans-differentiation into functionally and biologically active cells for use in therapeutic purposes. So far, progress regarding the use of both in vitro and in vivo regenerative medicine models already offers hope for the application of different types of stem cells as a powerful new therapeutic option to treat different diseases that were previously considered to be untreatable. Remarkable achievements in cell biology resulting in the isolation and characterization of various stem cells and progenitor cells has increased the expectation for the development of a new approach to the treatment of genetic and developmental human diseases. Due to the fact that currently stem cells and umbilical cord banks are so strictly defined and available, it seems that this mission is investigationally more practical than in the past. On the other hand, studies performed on stem cells, targeting their conversion into functionally mature tissue, are not necessarily seeking to result in the clinical application of the differentiated cells; In fact, still one of the important goals of these studies is to get acquainted with the natural process of development of mature cells from their immature progenitors during the embryonic period onwards, which can produce valuable results as knowledge of the developmental processes during embryogenesis. For example, the cellular and molecular mechanisms leading to mature and adult cells developmental abnormalities are relatively unknown. This lack of understanding stems from the lack of a good model system to study cell development and differentiation. Hence, the knowledge reached through these studies can prove to be a breakthrough in preventing developmental disorders. Meanwhile, many researchers conduct these studies to understand the molecular and cellular basis of cancer development. The fact that cancer is one of the leading causes of death throughout the world, highlights the importance of these researches in the fields of biology and medicine.
Medical Advancements in Aging and Regenerative Technologies: Clinical Tools and Applications
Edited by Andriani Daskalaki
August 22, 2012
This book focuses on the identification of basic mechanisms that are associated with aging, e.g. in the
bone and the skin, as well as tools and techniques applied in regenerative medicine. Aging is a process
guided by a large number of signaling molecules and gene regulatory factors acting to establish specific gene expression patterns. The mechanisms that lead to impaired healing with increasing age remain
largely unknown. Therefore, manipulation of key factors of regenerative processes within regulatory
networks should help to improve regeneration in a therapeutic setting.
Accordingly, an understanding of molecular and signaling mechanisms underlying the aging process
is likely to lead to novel approaches of preventing and treating age-related diseases. A combination of
high throughput approaches and advanced computational techniques to dissect the molecular mechanisms
of stem cell fate and cellular reprogramming are applied in regenerative medicine.
The aim of this publication is focused on the translation of basic science discoveries into regenerative
therapies, as well as the application of clinical tools in aging and tissue regeneration.
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